Gordon Research Conference on Molecular Pharmacology

EVENT DATE: 6/13/2023

​Invited speaker, Gordon Research Conference on Molecular Pharmacology, Les Diablerets, Switzerland, “Conformational Selection in ACKR3 Activation and Inhibition by Ligands Large and Small”.

At the ENC conference in California and at the Molecular Pharmacology GRC in Switzerland a few months later, Dr. Volkman presented findings from a recent NMR study carried out in his MCW research lab on the conformational regulation of the atypical chemokine receptor 3 (ACKR3). These results, which were published last year in Science, demonstrate that recruitment of beta arrestin involves the dampening of internal motions to stabilize the active state of the receptor.

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